Back HIV Treatment Search for a Cure

Search for a Cure

BHIVA 2015: Many People with HIV Willing to Take Part in Cure Research Despite its Risks

There is a strong interest among people living with HIV in research towards an HIV cure, with many potential participants willing to consider antiretroviral treatment interruption. Respondents to a survey presented at the British HIV Association (BHIVA) conference this week in Brighton generally understood that they would be unlikely to benefit personally from cure research. Priorities for a cure were to eliminate health problems and the risk of HIV transmission, rather than necessarily testing HIV-negative.

alt

Read more:

Long-time Researcher Discusses Myths About HIV Pathogenesis, Treatment, and Cure

Over the 3 decades of the epidemic a number of misconceptions have arisen about HIV infection, how the immune system fights the virus, and how best to treat and potentially cure it, along with a number of important questions that remain unanswered, according to an opinion article in the April 13 advance edition of Trends in Molecular Medicine by Jay Levy from the University of California at San Francisco, one of the first researchers to study HIV. The trend toward earlier antiretroviral therapy and treatment-as-prevention are among the issues he contests.

alt

Read more:

CROI 2015: Experimental Agents Reverse HIV Latency, Help Immune System Fight Infected Cells

Researchers at the recent 2015 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle presented data on several experimental agents that may play a role in achieving a "functional cure" for HIV, or prolonged remission without disease progression. These include drugs that reactivate the latent HIV reservoir, interfere with expression of viral DNA, and help the immune system target HIV-infected cells.

alt

Read more:

Trial of CCR5-Deleted Stem Cell Gene Therapy for HIV Gets FDA Go-Ahead

The U.S. Food and Drug Administration (FDA) has given approval to proceed with a clinical trial of a gene therapy method that cuts the gene for the CCR5 coreceptor out of stem cells, making them resistant to HIV entry, the California Institute for Regenerative Medicine (CIRM) recently announced.

alt

Read more:

CROI 2015: Researchers Discuss HIV Cure Strategies

Researchers at the recent 2015 Conference on Retroviruses and Opportunistic Infections in Seattle discussed a variety of approaches to achieve a functional cure, or prolonged remission of HIV. Most experts expect that a combination of multiple approaches will be needed.

Early Antiretroviral Treatment Reduces, but Does Not Eliminate HIV Reservoir

Experimental Agents Reverse HIV Latency, Help Immune System Fight Infected Cells

We May Need to Combine Many Approaches to Achieve a Cure for HIV

3/20/15

alt