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Search for a Cure

3. Renewed Focus on HIV Vaccines and Antibodies

Researchers intensified the search for novel types of therapies to prevent, treat, and potentially cure HIV, including immune-based strategies such as antibodies and vaccines.

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UCSF/amfAR HIV Cure Summit Reviews Progress in Cure-Related Research

Researchers at the amfAR Institute for HIV Cure Research at the University of California at San Francisco (UCSF) presented an update on their latest cure-related work at a World AIDS Day summit on December 1. This multidisciplinary effort aims to understand HIV reservoirs within the body and ultimately to control or eliminate the virus.alt

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Media Reports of a British HIV Cure Breakthrough Are Premature

The Sunday Times yesterday reported that HIV had become undetectable in the blood of one man taking part in the RIVER study, a trial of an intensive treatment regimen designed to test whether it is possible to reduce levels of HIV-infected cells in the bodies of people recently infected with HIV. The Sunday Times reported that British scientists are on the "brink of an HIV cure." But in fact, the study is still in its early stages, participants are still on antiretroviral treatment, and it will not be able to describe participants as "cured" until extensive follow-up has taken place.

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Researchers Observe Sustained Remission in Monkeys with HIV-Like Virus

Researchers have induced sustained remission of simian immune deficiency virus (SIV), a relative of HIV, in macaque monkeys treated with antiretroviral therapy (ART) and an antibody-based therapy used to treat inflammatory bowel disease, according to a report in the October 14 edition of Science. The monkeys not only had undetectable viral load for up to nearly 2 years after stopping treatment, but they also showed replenishment of key immune cells in the gut.

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AIDS 2016: Realism Needed About the Benefits and Risks of Taking Part in HIV Cure Research

A significant proportion of people living with HIV would be willing to take part in a study towards a cure for HIV, according to research presented at the recent 21st International AIDS Conference (AIDS 2016) in Durban. However, some potential participants may not fully understand that taking part in an early-phase study is highly unlikely to afford any personal clinical benefit, but might have the potential to cause harm.

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