Back HIV Prevention Pre-exposure (PrEP)

Pre-exposure Prophylaxis (PrEP)

CROI 2017: Bacterial Vaginosis Does Not Affect Efficacy of Oral PrEP in Women

Research presented at the Conference on Retroviruses and Opportunistic Infections last month in Seattle found that the efficacy of oral pre-exposure prophylaxis (PrEP) for women was not affected by bacterial vaginosis (BV) -- the overgrowth in the vagina of untypical microbes. The effectiveness of PrEP in the Partners PrEP study was not significantly different in women with and without BV. This rules out BV as a possible cause for the lower effectiveness of oral PrEP in some studies of women compared to studies of men who have sex with men.

alt

Read more:

CROI 2017: STI Rates Among PrEP Users Are High, But Evidence that PrEP Increases Them Is Inconclusive

A study of pre-exposure prophylaxis (PrEP) users presented at the Conference on Retroviruses and Opportunistic Infections this month in Seattle showed that they had very high rates of sexually transmitted infection (STI) diagnosis -- on the order of 20 times higher than among HIV-negative gay men in the general population. However, it is unclear whether STIs increased further after people went on PrEP.

alt

Read more:

CROI 2017: STI Prophylaxis in PrEP Users Reduces Syphilis and Chlamydia, but Not Gonorrhea

Use of the antibiotic doxycycline as on-demand post-exposure prophylaxis by men who have sex with men taking part in the Ipergay HIV PrEP trial produced a 70% drop in chlamydia infections and a 73% drop in syphilis, but no reduction in gonorrhea, according to a late-breaking report at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) this week in Seattle.

alt

Read more:

CROI 2017: Unique Case of PrEP Failure Without Drug Resistance Reported in Amsterdam

HIV pre-exposure prophylaxis (PrEP) appears to be nearly 100% effective if taken consistently. However, among tens of thousands of cases of PrEP preventing HIV, there have been a few reports of people who acquired HIV despite high adherence to PrEP and adequate drug levels, including one reported in a poster at the Conference on Retroviruses and Opportunistic Infections (CROI 2017) last week in Seattle.

alt

Read more:

Hope Overshadowed -- The National HIV PrEP Summit

The U.S. National HIV PrEP Summit, which took place in early December in San Francisco, was designed as an event of celebration and hope. Its structure, its speakers, even the way the plenary room was designed and the way the speakers dressed, all conveyed one message: we are all in this together, and pre-exposure prophylaxis (PrEP) really is the game-changer we have been looking for.

alt

Read more: