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Pre-exposure Prophylaxis (PrEP)

More iPrEx and OLE Data Published: Adherence Higher in U.S.

Participants enrolled at the U.S. study sites of the global iPrEx trial of Truvada pre-exposure prophylaxis (PrEP) achieved better adherence than those in other countries, reaching 90% in San Francisco, researchers reported in the September 16 advance edition of Journal of Acquired Immune Deficiency Syndromes. Findings from the iPrEx open-label extension (OLE) were also recently published.

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PrEP Rally: As Numbers Rise, Advocates Want Wider Access

The number of people using pre-exposure prophylaxis, or PrEP, to prevent HIV infection has risen steadily over the past year, according to data presented this week at a San Francisco community engagement forum. But PrEP advocates -- including 3 city supervisors -- say more needs to be done to overcome barriers to access for all who want it.

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PrEP by the Numbers: Interpreting Conflicting Study Data

A recent ad campaign from the AIDS Healthcare Foundation has kicked of a new round of controversy about HIV pre-exposure prophylaxis (PrEP) and how to interpret apparently conflicting numbers from prevention studies.

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ICAAC 2014: Tenofovir Vaginal Ring and Nanoparticle Gel Are Protective in Animal Studies

A vaginal ring that dispenses tenofovir protected all 6 macaque monkeys exposed to an HIV-like virus, while a heat-sensitive vaginal gel containing tenofovir nanoparticles prevented infection of mice, researchers reported at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy last week in Washington, DC.

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Counseling Helps Improve PrEP Adherence Among Serodiscordant Couples

Cognitive-behavioral counseling sessions significantly increased the likelihood of consistently taking pills among participants with faltering adherence in an African trial of Truvada pre-exposure prophylaxis (PrEP) for serodiscordant (mixed HIV status) heterosexual couples, according to a report in the August 15 Journal of Acquired Immune Deficiency Syndromes.

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